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Article

Ovarian Stem Cell Niche and Follicular Renewal in Mammals

28 Jun 2011

Abstract excerpt

Stem cell niche consists of perivascular compartment, which connects the stem cells to the immune and vascular systems. During embryonic period, extragonadal primordial germ cells colonize coelomic epithelium of developing gonads. Subsequently, ovarian stem cells (OSC) produce secondary germ cells under the influence of OSC niche, including immune system-related cells and hormonal signaling. The OSC in fetal and...

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PMID: 21714105
DOI: 10.1002/ar.21422

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