Article
HLA Genotype and Probiotics Modify the Association Between Timing of Solid Food Introduction and Islet Autoimmunity in the TEDDY Study.
Diabetes care - 1 Oct 2023
Uusitalo Ulla, Mramba Lazarus K, Aronsson Carin Andrén, Vehik Kendra, Yang Jimin, Hummel Sandra, Lernmark Åke, Rewers Marian, Hagopian William, McIndoe Richard, Toppari Jorma, Ziegler Anette-G, Akolkar Beena, Krischer Jeffrey P, Virtanen Suvi M, Norris Jill M
Abstract excerpt
OBJECTIVE: To study the interaction among HLA genotype, early probiotic exposure, and timing of complementary foods in relation to risk of islet autoimmunity (IA). RESEARCH DESIGN AND METHODS: The Environmental Determinants of Diabetes in the Young (TEDDY) study prospectively follows 8,676 children with increased genetic risk of type 1 diabetes. We used a Cox proportional hazards regression model adjusting for...
Topics
Join the communities discussing this publication.