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Article

BMP2 is a potential causative gene for isolated dextrocardia situs solitus.

European journal of medical genetics - 1 Sept 2023

Yogi Analia, Iemura Ryosei, Nakatani Hisae, Takasawa Kei, Gau Maki, Yamauchi Takeru, Yoshida Masayuki, Moriyama Keiji, Ishii Taku, Hosokawa Susumu, Yamada Mamiko, Suzuki Hisato, Kosaki Kenjiro, Kashimada Kenichi, Morio Tomohiro

Abstract excerpt

BMP2 (bone morphogenic protein-2) is a member of the TGF-β superfamily and has essential roles in the development of multiple organs, including osteogenesis. Because of its crucial role in organ and skeletal development, Bmp2 null mice is fetal lethal. The recent report has characterized multiple patients with BMP2 haploinsufficiency, describing individuals with BMP2 sequence variants and deletions associated...

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PMID: 37572998
DOI: 10.1016/j.ejmg.2023.104820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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