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Bioengineered three‐dimensional co‐culture of cancer cells and endothelial cells: A model system for dual analysis of tumor growth and angiogenesis

28 Mar 2017

Abstract excerpt

Angiogenesis marks the transformation of a benign local tumor into a life-threatening disease. Many in vitro assays are available on two-dimensional (2D) platforms, however, limited research has been conducted to investigate the behavior of tumors and endothelial cells (ECs) grown on three-dimensional (3D) platforms. This study provides a 3D co-culture spheroid of tumor cells with ECs to study the interplay...

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PMID: 28369747
DOI: 10.1002/bit.26297

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