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Tumor cells and their crosstalk with endothelial cells in 3D spheroids

30 Aug 2017

Abstract excerpt

Recapitulating the tumor microenvironment is a central challenge in the development of experimental model for cancer. To provide a reliable tool for drug development and for personalized cancer therapy, it is critical to maintain key features that exist in the original tumor. Along with this effort, 3-dimentional (3D) cellular models are being extensively studied. Spheroids are self-assembled cell aggregates that...

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PMID: 28874803
DOI: 10.1038/s41598-017-10699-y

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