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Article

A comprehensive analysis of Fanconi anemia genes in Chinese patients with high-risk hereditary breast cancer.

Journal of cancer research and clinical oncology - 1 Nov 2023

Zhu Qiao-Yan, Li Pu-Chun, Zhu Yi-Fan, Pan Jia-Ni, Wang Rong, Li Xiao-Lin, Ye Wei-Wu, Ding Xiao-Wen, Wang Xiao-Jia, Cao Wen-Ming

Abstract excerpt

BACKGROUND: Four Fanconi anemia (FA) genes (BRCA1, BRCA2, PALB2 and RAD51C) are defined as breast cancer (BC) susceptibility genes. Other FA genes have been inconsistently associated with BC. Thus, the role of other FA genes in BC should be explored in specific populations. METHODS: Mutations in 16 FA genes were screened with a 98-gene panel sequencing assay in a cohort of 1481 Chinese patients with high-risk...

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Source

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Identifiers

PMID: 37566130
DOI: 10.1007/s00432-023-05236-6
PMCID: PMC10590287

Genes

BRCA1
BRCA2
BRIP1
FANCA
FANCB
FANCD2
FANCM
PALB2
RAD51C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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