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Article

Whole genome sequencing identifies allelic ratio distortion in sperm involving genes related to spermatogenesis in a swine model.

DNA research : an international journal for rapid publication of reports on genes and genomes - 3 Dec 2020

Gòdia Marta, Casellas Joaquim, Ruiz-Herrera Aurora, Rodríguez-Gil Joan E, Castelló Anna, Sánchez Armand, Clop Alex

Abstract excerpt

Transmission Ratio Distortion (TRD), the uneven transmission of an allele from a parent to its offspring, can be caused by allelic differences affecting gametogenesis, fertilization or embryogenesis. However, TRD remains vaguely studied at a genomic scale. We sequenced the diploid and haploid genomes of three boars from leukocytes and spermatozoa at 50x to shed light into the genetic basis of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32931559
DOI: 10.1093/dnares/dsaa019
PMCID: PMC7750926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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