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Spatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer

8 Aug 2023

Abstract excerpt

Esophageal squamous precancerous lesions (ESPL) are the precursors of esophageal squamous cell carcinoma (ESCC) including low-grade and high-grade intraepithelial neoplasia. Due to the absence of molecular indicators, which ESPL will eventually develop into ESCC and thus should be treated is not well defined. Indicators, for predicting risks of ESCC at ESPL stages, are an urgent need. We perform spatial...

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PMID: 37553345
DOI: 10.1038/s41467-023-40343-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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