Article
Real-World Treatment Patterns in Patients With HER2-Amplified Metastatic Colorectal Cancer: A Clinical-Genomic Database Study.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Aug 2023
Strickler John H, Hsu Ling-I, Wright Phoebe, Stecher Michael, Siadak Muriel F, Palanca-Wessels Maria Corinna, Yu Junhua, Zhang Nicole, Espenschied Carin R, Lang Kathryn, Bekaii-Saab Tanios S
Abstract excerpt
BACKGROUND: HER2 amplification (HER2+) occurs in approximately 3% of patients with metastatic colorectal cancer (mCRC). Despite the recent addition of HER2-directed therapies to treatment recommendations in the NCCN Guidelines, until more recently there were no FDA-approved treatments. This study examined real-world treatment patterns in patients with HER2+ mCRC in the United States before and after the emerging...
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