Article

Comprehensive Genomic Profiling in Metastatic Solid Tumors: High Actionability But Low Implementation in Real-World Practice

2026-06-05

Abstract excerpt

<title>Abstract</title> <p> Background Comprehensive genomic profiling (CGP) identifies actionable alterations in two-thirds of metastatic solid tumors, yet real-world treatment implementation remains unknown. We characterized both genomic yield and clinical translation barriers in 111 consecutive patients across 19 tumor types to quantify the precision oncology "knowing-doing gap." Methods We performed retros...

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Literature Corpus work: 170ba9c9-0a0a-5ae8-97fe-b9a305e38736
DOI: 10.21203/rs.3.rs-9878895/v1

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