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Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions

3 Aug 2023

Abstract excerpt

BACKGROUND: Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus affects the brain and how the mutations carried by the different variants modulate those neurological symptoms remain unclear. METHODS: We used primary human pericytes, foetal astrocytes, endothelial cells and a microglial cell line to...

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PMID: 37537664
DOI: 10.1186/s12974-023-02861-3

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