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SARS-CoV-2 productively infects human brain microvascular endothelial cells

15 Jun 2022

Abstract excerpt

BACKGROUND: The emergence of the novel, pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global health emergency. SARS-CoV-2 is highly contagious and has a high mortality rate in severe patients. However, there is very limited information on the effect of SARS-CoV-2 infection on the integrity of the blood-brain barrier (BBB). METHODS: RNA-sequencing profiling was performed to...

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PMID: 35705998
DOI: 10.1186/s12974-022-02514-x

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