Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of SIRT2 inhibition on the aging process of brain in male rats

1 Jan 2023

Abstract excerpt

Background: )-dependent deacetylases, sirtuin 2 (SIRT2) has been associated to age-related diseases. However, the exact role of SIRT2 in brain aging is not well studied. The objective of the current study was to study the role of SIRT2 inhibition on brain aging through the neuroprotective mechanisms. Methods: We tested the effects of AGK-2, a SIRT2 inhibitor, on oxidative stress parameters, apoptosis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Silymarin and Mushroom Poisoning
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37519449
DOI: 10.1016/j.nbas.2023.100087

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of SIRT2 inhibition on the aging process of brain in male ratsPMID 37519449Read ↗

Age-Associated Changes of Sirtuin 2 Expression in CNS and the PeripherySemantic proximity Read ↗

SIRT2 as a Therapeutic Target for Age-Related DisordersSemantic proximity Read ↗

SIRT1 and SIRT2 Activity Control in Neurodegenerative DiseasesSemantic proximity Read ↗

Review of the anti-inflammatory effect of SIRT1 and SIRT2 modulators on neurodegenerative diseases.Semantic proximity Read ↗

Sirtuins, a key regulator of ageing and age-related neurodegenerative diseasesSemantic proximity Read ↗

SIRT2 as a potential new therapeutic target for Alzheimer’s diseaseSemantic proximity Read ↗

SIRT2 in age-related neurodegenerative disorders.Semantic proximity Read ↗

Understanding the Potential Role of Sirtuin 2 on Aging: Consequences of SIRT2.3 Overexpression in SenescenceSemantic proximity Read ↗

Sirtuin activators as an anti-aging intervention for longevitySemantic proximity Read ↗

The sirtuin family’s role in aging and age-associated pathologiesSemantic proximity Read ↗

Sirtuin 2 (SIRT2): Confusing Roles in the Pathophysiology of Neurological DisordersSemantic proximity Read ↗

SIRT1 as a therapeutic target for Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.