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Article

Optimizing Antiretroviral Therapy in Heavily ART-Experienced Patients with Multi-Class Resistant HIV-1 Using Proviral DNA Genotypic Resistance Testing.

Viruses - 27 Jun 2023

Rauschning Dominic, Ehren Ira, Heger Eva, Knops Elena, Fätkenheuer Gerd, Suárez Isabelle, Lehmann Clara

Abstract excerpt

Resistance to multiple antiretroviral drugs among people living with HIV (PLWH) can result in a high pill burden, causing toxicity and drug interactions. Thus, the goal is to simplify treatment regimens while maintaining effectiveness. However, former resistance analysis data may not be current or complete. The use of proviral DNA genotyping may assist in selecting appropriate treatment options. A retrospective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37515133
DOI: 10.3390/v15071444
PMCID: PMC10384096

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