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Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning

22 Jun 2022

Abstract excerpt

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases, which significantly impact the quality of life. Transcriptome-wide association study (TWAS) was conducted to estimate both transcriptomic and genomic features of AD and detected significant associations between 31 expression quantitative loci and 25 genes. Our results replicated well-known genetic markers for AD, as well as 4 novel...

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PMID: 35729261
DOI: 10.1038/s42003-022-03564-w

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