Article
Frequency of polymorphisms in the CYP2C9, VKORC1, and CYP4F2 genes related to the metabolism of Warfarin in healthy donors from Cali, Colombia.
Medicine - 28 Jul 2023
Giraldo-Ocampo Sebastian, Diaz-Ordoñez Lorena, Silva-Cuero Yisther Katherine, Gutierrez-Medina Juan David, Candelo Estephania, Diaz Javier A, Pachajoa Harry
Abstract excerpt
Alleles in the VKORC1, CYP2C9, and CYP4F2 genes can influence Warfarin dose requirement. We aimed to determine the frequency of the polymorphisms in these genes in healthy individuals from Cali, Colombia. Observational study where total blood was collected from 107 healthy donors who attended a higher educational institution in Cali, Colombia. Sanger sequencing of exons 2, 3, 5, and 7 of the CYP2C9 gene; the...
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