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Article

A threshold for mitotic activity and post-surgical residual volume defines distinct prognostic groups for astrocytoma IDH-mutant.

Neuropathology and applied neurobiology - 1 Aug 2023

Tran Suzanne, Thomas Alice, Aliouat Ilyes, Karachi Carine, Lozano Fernando, Mokhtari Karima, Dehais Caroline, Feuvret Loïc, Carpentier Catherine, Giry Marine, Doukani Abiba, Lerond Julie, Marie Yannick, Sanson Marc, Idbaih Ahmed, Carpentier Alexandre, Hoang-Xuan Khê, Touat Mehdi, Capelle Laurent, Bielle Franck

Abstract excerpt

AIMS: The distinction between CNS WHO grade 2 and grade 3 is instrumental in choosing between observational follow-up and adjuvant treatment for resected astrocytomas IDH-mutant. However, the criteria of CNS WHO grade 2 vs 3 have not been updated since the pre-IDH era. METHODS: Maximal mitotic activity in consecutive high-power fields corresponding to 3 mm2 was examined for 118 lower-grade astrocytomas...

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PMID: 37503540
DOI: 10.1111/nan.12928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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