Article
Prognostic and radiographic correlates of a prospectively collected molecularly profiled cohort of IDH1/2-wildtype astrocytomas.
Brain pathology (Zurich, Switzerland) - 1 May 2020
Lin Andrew L, Rosenblum Marc, Mellinghoff Ingo K, Tabar Viviane S, Ogilvie Shahiba, Schaff Lauren, Yang Tzu-I Jonathan, Young Robert J, Taylor Barry S, Jonsson Philip, Bale Tejus A
Abstract excerpt
BACKGROUND: In the molecular era, the relevance of tumor grade for prognostication of IDH1/2-wildtype (WT) gliomas has been debated. It has been suggested that histologic grade II and III astrocytomas with molecular features of glioblastoma, IDH1/2-WT have a similar prognosis to glioblastoma and should be considered for the same clinical trials. METHODS: We integrated prospective clinical sequencing from 564...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.