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Article

Association of PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms with pulmonary tuberculosis susceptibility in a Chinese population.

Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2023

He Juan, Liu Shengyuan, Guo Xujun, Zhang Fan, Fan Yuzheng, Wu Lijuan, Takiff Howard Eugene, Zhao Yashuang

Abstract excerpt

BACKGROUND: Autophagy can inhibit the survival of intracellular microorganisms including Mycobacterium tuberculosis (Mtb), and the PI3K/AKT/mTOR pathway plays a crucial role. This study investigated the association between PI3K/AKT/mTOR pathway autophagy-related gene polymorphisms and pulmonary tuberculosis (PTB) susceptibility. METHODS: KEGG pathway and gene ontology (GO) databases were searched for genes...

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Identifiers

PMID: 37493735
DOI: 10.1590/0037-8682-0104-2023
PMCID: PMC10367219

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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