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Development of a four autophagy-related gene signature for active tuberculosis diagnosis

23 May 2025

Abstract excerpt

Background: Tuberculosis (TB) diagnostics urgently require non-sputum biomarkers to address the limitations of conventional methods in distinguishing active TB (ATB) from latent infection (LTBI), healthy controls (HCs), and TB-mimicking diseases (ODs, other diseases). Methods: Transcriptomic data from GSE83456 and GSE152532 were combined to form the selection dataset. Marker genes were identified from...

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PMID: 40487315
DOI: 10.3389/fcimb.2025.1600348

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