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Article

Germline Mutations in 12 Genes and Risk of Ovarian Cancer in Three Population-Based Cohorts.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 2 Oct 2023

Kotsopoulos Joanne, Hathaway Cassandra A, Narod Steven A, Teras Lauren R, Patel Alpa V, Hu Chunling, Yadav Siddhartha, Couch Fergus J, Tworoger Shelley S

Abstract excerpt

BACKGROUND: With the widespread use of multigene panel genetic testing, population-based studies are necessary to accurately assess penetrance in unselected individuals. We evaluated the prevalence of germline pathogenic or likely pathogenic variants (mutations) in 12 cancer-predisposition genes and associations with ovarian cancer risk in three population-based prospective studies [Nurses' Health Study (NHS),...

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Identifiers

PMID: 37493628
DOI: 10.1158/1055-9965.EPI-23-0041
PMCID: PMC10592229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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