Article
Identifying the personalized driver gene sets maximally contributing to abnormality of transcriptome phenotype in glioblastoma multiforme individuals.
Molecular oncology - 1 Nov 2023
Xu Jinyuan, Pang Bo, Lan Yujia, Dou Renjie, Wang Shuai, Kang Shaobo, Zhang Wanmei, Liu Yuanyuan, Zhang Yijing, Ping Yanyan
Abstract excerpt
High heterogeneity in genome and phenotype of cancer populations made it difficult to apply population-based common driver genes to the diagnosis and treatment of cancer individuals. Characterizing and identifying the personalized driver mechanism for glioblastoma multiforme (GBM) individuals were pivotal for the realization of precision medicine. We proposed an integrative method to identify the personalized...
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