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Article

Spatial transcriptomics of human placentas reveal distinct RNA patterns associated with morphology and preeclampsia

5 Jul 2023

Abstract excerpt

Spatial transcriptomics (ST) maps RNA level patterns within a tissue. This technology has not been previously applied to human placental tissue. We demonstrate analysis of human placental samples with ST. Unsupervised clustering revealed that distinct RNA patterns were found corresponding to different morphological structures. Additionally, when focusing upon terminal villi and hemoglobin associated structures,...

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PMID: 37481829
DOI: 10.1016/j.placenta.2023.07.004

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