Article
Integrative single-cell and cell-free plasma RNA transcriptomics elucidates placental cellular dynamics
22 Aug 2017
Abstract excerpt
The human placenta is a dynamic and heterogeneous organ critical in the establishment of the fetomaternal interface and the maintenance of gestational well-being. It is also the major source of cell-free fetal nucleic acids in the maternal circulation. Placental dysfunction contributes to significant complications, such as preeclampsia, a potentially lethal hypertensive disorder during pregnancy. Previous studies...
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