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Article

The role of germline and somatic mutations in predicting cancer-associated thrombosis: a narrative review.

Current opinion in hematology - 1 May 2025

Lanting Vincent, Oskam Merel, Wilmink Hanneke, Kamphuisen Pieter W, van Es Nick

Abstract excerpt

PURPOSE OF REVIEW: Patients with cancer have an increased risk of venous thromboembolism (VTE). Guidelines suggest to use risk assessment tools to guide decisions about thromboprophylaxis, but current tools have modest discriminatory ability. Genetic information from the germline or tumor has the potential to improve VTE prediction. Here, we provide a clinical overview of the current role of genetics in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39851266
DOI: 10.1097/MOH.0000000000000861
PMCID: PMC11957438

Genes

ALK
CDKN2B
CTNNB1
IDH1
KEAP1
KRAS
MET
STK11

Provenance

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