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Growth exponents reflect evolutionary processes and treatment response in brain metastases

21 Jul 2023

Abstract excerpt

Tumor growth is the result of the interplay of complex biological processes in huge numbers of individual cells living in changing environments. Effective simple mathematical laws have been shown to describe tumor growth in vitro, or simple animal models with bounded-growth dynamics accurately. However, results for the growth of human cancers in patients are scarce. Our study mined a large dataset of 1133 brain...

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PMID: 37479705
DOI: 10.1038/s41540-023-00298-1

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