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Article

SARS-CoV-2 protein structure and sequence mutations: Evolutionary analysis and effects on virus variants.

PloS one - 1 Jan 2023

Lomoio Ugo, Puccio Barbara, Tradigo Giuseppe, Guzzi Pietro Hiram, Veltri Pierangelo

Abstract excerpt

The structure and sequence of proteins strongly influence their biological functions. New models and algorithms can help researchers in understanding how the evolution of sequences and structures is related to changes in functions. Recently, studies of SARS-CoV-2 Spike (S) protein structures have been performed to predict binding receptors and infection activity in COVID-19, hence the scientific interest in the...

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Identifiers

PMID: 37471335
DOI: 10.1371/journal.pone.0283400
PMCID: PMC10358949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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