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Network analysis uncovers the communication structure of SARS-CoV-2 spike protein identifying sites for immunogen design

26 Dec 2022

Abstract excerpt

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has triggered myriad efforts to understand the structure and dynamics of this complex pathogen. The spike glycoprotein of SARS-CoV-2 is a significant target for immunogens as it is the means by which the virus enters human cells, while simultaneously sporting mutations responsible for immune escape. These functional and escape processes are regulated by...

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PMID: 36590900
DOI: 10.1016/j.isci.2022.105855

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