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Mitochondrial Genome-Encoded Long Noncoding RNA Cytochrome B and Mitochondrial Dysfunction in Diabetic Retinopathy

19 Jul 2023

Abstract excerpt

Aims: Mitochondrial dysfunction is closely associated with the development of diabetic complications. In diabetic retinopathy, electron transport chain is compromised and mitochondrial DNA (mtDNA) is damaged, downregulating transcription of mtDNA-encoded cytochrome B ( CYTB ) and its antisense long noncoding RNA, long noncoding RNA cytochrome B (Lnc CytB ). Our goal was to investigate the role of Lnc CytB in the...

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PMID: 37464864
DOI: 10.1089/ars.2023.0303

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