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Article

Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing

15 Jul 2023

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37460052
DOI: 10.1016/j.ejphar.2023.175916

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Related research

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Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editingPMID 37460052Read ↗

RNA Editing in Neurological and Neurodegenerative Disorders.Semantic proximity Read ↗

Induced Loss of ADAR2 Engenders Slow Death of Motor Neurons from Q/R Site-Unedited GluR2Semantic proximity Read ↗

Novel ADAR2 variants in children with seizures, intellectual disability, and motor delay have reduced RNA editing.Semantic proximity Read ↗

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The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer’s diseaseSemantic proximity Read ↗

Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy.Semantic proximity Read ↗

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RNA editing: a molecular mechanism for the fine modulation of neuronal transmission.Semantic proximity Read ↗

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Hippocampus-specific deficiency in RNA editing of GluA2 in Alzheimer's disease.Semantic proximity Read ↗

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicitySemantic proximity Read ↗

ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo.Semantic proximity Read ↗

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