Article
Association between matrix metalloproteinase-3 polymorphism and anterior cruciate ligament ruptures.
Genetics and molecular research : GMR - 31 Oct 2011
Malila S, Yuktanandana P, Saowaprut S, Jiamjarasrangsi W, Honsawek S
Abstract excerpt
Anterior cruciate ligament (ACL) ruptures are considered to be the most severe joint injury in sports. However, the precise etiologies of ACL injuries are not fully understood. Recently, the gene encoding the matrix metalloproteinase-3 (MMP-3, stromelysin-1) was shown to be associated with anterior cruciate ligament ruptures. The 5A/6A polymorphism in the promoter of the MMP-3 gene affects the regulation of...
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