Article
NLRP3 inflammasome (rs10754558) gene polymorphism in patients with atopic dermatitis.
The Egyptian journal of immunology - 1 Jul 2023
El Gendy Aya, Abo Ali Fawzia H, Baioumy Shereen A, Taha Sara I, El-Bassiouny Mahy, Abdel Latif Osama M
Abstract excerpt
The nucleotide-binding oligomerization domain-like receptor 3 (NLRP3) inflammasome is a high molecular weight protein complex that has been linked to a variety of allergic and inflammatory disorders in humans, including atopic dermatitis (AD). Polymorphisms in NLRP3 genes could lead to immune dysregulation. This case-control study aimed to assess the association between NLRP3 inflammasome (rs10754558) gene...
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