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Article

Early-onset childhood atopic dermatitis is related to NLRP2 repression

9 Dec 2017

Abstract excerpt

Atopic dermatitis (AD) is a common skin disease in children. While genetic predisposition and environmental factors are accepted mediators of AD development, the role of the innate immune system is not yet completely elucidated. Likely mediators of AD are nucleotide-binding oligomerization and pyrin domain containing-receptors (NLRPs), which are involved in the innate immune response.1 So far, few studies...

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PMID: 29233739
DOI: 10.1016/j.jaci.2017.11.018

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