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Article

Association of NLRP3 rs10754558 polymorphism with inflammasome-related cytokine responses in chronic spontaneous urticaria.

Frontiers in immunology - 1 Jan 2026

Hammad Noha M, Ali Arwa O, Nofal Hagar, Mohamed Noura Mostafa, Gheith Tarek

Abstract excerpt

Background: Chronic spontaneous urticaria (CSU) is a clinically heterogeneous inflammatory condition affecting the skin, in which mechanisms beyond histamine-mediated mast cell activation are increasingly recognized. Dysregulation of innate immune pathways, including inflammasome signaling, may contribute to disease pathogenesis. Within the inflammasome family, NOD-like receptor pyrin domain-containing protein 3...

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Identifiers

PMID: 42183250
DOI: 10.3389/fimmu.2026.1804228
PMCID: PMC13194015

Genes

NLRP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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