Article
CCND2 mutations in atypical chronic myeloid leukemia: a report of two cases.
Leukemia & lymphoma - 1 Oct 2023
Iaquinta Giovanni, Scalzulli Emilia, Angeloni Silvia, Carmosino Ida, Costa Alessandro, Ielo Claudia, Passucci Mauro, Masucci Chiara, Martelli Maurizio, Grammatico Paola, Breccia Massimo
Abstract excerpt
Atypical chronic myeloid leukemia (aCML) is a rare MDS/MPN disease characterized by the absence of BCR::ABL1 rearrangement and well known typical mutations associated with myeloproliferative disorders. Mutational landscape associated with this disease was recently described with frequent involvement of SETBP1 and ETNK1 mutations. CCND2 mutations have not been frequently detected in MPN or MDS/MPN patients. We...
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