Article
Protein network analysis links the NSL complex to Parkinson's disease via mitochondrial and nuclear biology.
Molecular omics - 25 Sept 2023
Kelly Katie, Lewis Patrick A, Plun-Favreau Helene, Manzoni Claudia
Abstract excerpt
Whilst the majority of Parkinson's Disease (PD) cases are sporadic, much of our understanding of the pathophysiological basis of the disease can be traced back to the study of rare, monogenic forms of PD. In the past decade, the availability of genome-wide association studies (GWAS) has facilitated a shift in focus, toward identifying common risk variants conferring increased risk of developing PD across the...
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