Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Are novel treatments for brain disorders hiding in plain sight?

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2024

Duncan Laramie, Deisseroth Karl

Abstract excerpt

Psychiatric diseases are strongly influenced by genetics, but genetically guided treatments have been slow to develop, and precise molecular mechanisms remain mysterious. Although individual locations in the genome tend to not contribute powerfully to psychiatric disease incidence, genome-wide association studies (GWAS) have now successfully linked hundreds of specific genetic loci to psychiatric disorders [1-3]....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Diseases
Share to CHRNB4 gene
Share to Genetic Loci

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, Nicotinic

Source

Open in PubMed Open full text

Identifiers

PMID: 37422511
DOI: 10.1038/s41386-023-01636-x
PMCID: PMC10700299

Genes

ADH1B
ADH1C
ADH7
CHRNA3
CHRNA5
CHRNB4
DRD2
TACR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Are novel treatments for brain disorders hiding in plain sight?PMID 37422511Read ↗

Your genes are conspiring against you.Semantic proximity Read ↗

Common single nucleotide variants underlying drug addiction: more than a decade of research.Semantic proximity Read ↗

Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubricSemantic proximity Read ↗

New technologies provide insights into genetic basis of psychiatric disorders and explain their co-morbidity.Semantic proximity Read ↗

Is anxiety a pathway to Alcohol Use Disorders? A phenome-wide association study of the<i>GABRA2</i>coding variant rs279858Semantic proximity Read ↗

Recent progress in psychiatric genetics-some hope but no hype.Semantic proximity Read ↗

Linking GWAS to pharmacological treatments for psychiatric disordersSemantic proximity Read ↗

Human Genetics of Addiction: New Insights and Future Directions.Semantic proximity Read ↗

Neuroscience and Genetic: Can They Be a Faustian Bargain for Addictive Behaviours Research and Treatment?Semantic proximity Read ↗

Gene-Gene interactions and pleiotropy in the brain nicotinic pathway associated with the heaviness and precocity of tobacco smoking among outpatients with multiple substance use disordersSemantic proximity Read ↗

Genetic Relationship between Schizophrenia and Nicotine Dependence.Semantic proximity Read ↗

Genetic risk prediction and neurobiological understanding of alcoholism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.