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Crosstalk between autophagy and CSCs: molecular mechanisms and translational implications

8 Jul 2023

Abstract excerpt

Cancer stem cells(CSCs) play a key role in regulating tumorigenesis, progression, as well as recurrence, and possess typical metabolic characteristics. Autophagy is a catabolic process that can aid cells to survive under stressful conditions such as nutrient deficiency and hypoxia. Although the role of autophagy in cancer cells has been extensively studied, CSCs possess unique stemness, and their potential...

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PMID: 37422448
DOI: 10.1038/s41419-023-05929-3

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