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Article

The Roles of Autophagy in Cancer

5 Nov 2018

Abstract excerpt

Autophagy is an intracellular degradative process that occurs under several stressful conditions, including organelle damage, the presence of abnormal proteins, and nutrient deprivation. The mechanism of autophagy initiates the formation of autophagosomes that capture degraded components and then fuse with lysosomes to recycle these components. The modulation of autophagy plays dual roles in tumor suppression and...

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PMID: 30400561
DOI: 10.3390/ijms19113466

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