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Article

Targeting autophagy in cancer stem cells as an anticancer therapy.

Cancer letters - 1 May 2017

Lei Yuanyuan, Zhang Dan, Yu Jin, Dong Hui, Zhang Jianwei, Yang Shiming

Abstract excerpt

Cancer stem cells (CSCs), which comprise a small proportion of total cancer cells, have special capacities for self-renewal, differentiation and tumor formation. Currently, CSCs are regarded as the major cause of the failure in anticancer therapy, such as chemoresistance and/or radioresistance, tumor recurrence and metastasis. Autophagy, a process of cellular self-digestion and response to stress, has a role in...

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Identifiers

PMID: 28216370
DOI: 10.1016/j.canlet.2017.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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