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Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell

6 Jul 2023

Abstract excerpt

Trophectoderm cells of the blastocyst are the precursor of the placenta that is comprised of trophoblast, endothelial and smooth muscle cells. Since trophoectoderm cells are epithelial in nature, epithelial mesenchymal transition (EMT) of trophoblast stem (TS) cells might play pivotal role in placental morphogenesis. However, the molecular regulation of EMT during placental development and trophoblast...

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PMID: 37414855
DOI: 10.1038/s41598-023-37977-2

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