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BMP4 regulation of human trophoblast development

1 Jan 2014

Abstract excerpt

Since the derivation of human embryonic stem cells, and the subsequent generation of induced pluripotent stem cells, there has been much excitement about the ability to model and evaluate human organ development in vitro. The finding that these cells, when treated with BMP4, are able to generate the extraembryonic cell type, trophoblast, which is the predominant functional epithelium in the placenta, has not been...

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PMID: 25023690
DOI: 10.1387/ijdb.130341mp

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