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Specification of trophoblast from embryonic stem cells exposed to BMP4†

22 Mar 2018

Abstract excerpt

Trophoblast (TB) comprises the outer cell layers of the mammalian placenta that make direct contact with the maternal uterus and, in species with a highly invasive placenta, maternal blood. It has its origin as trophectoderm, a single epithelial layer of extra-embryonic ectoderm that surrounds the embryo proper at the blastocyst stage of development. Here, we briefly compare the features of TB specification and...

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PMID: 29579154
DOI: 10.1093/biolre/ioy070

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