Article
Association of Risk Variants in the CFH Gene With Elevated Levels of Coagulation and Complement Factors in Idiopathic Multifocal Choroiditis.
JAMA ophthalmology - 1 Aug 2023
de Groot Evianne L, Ossewaarde-van Norel Jeannette, de Boer Joke H, Hiddingh Sanne, Bakker Bjorn, van Huet Ramon A C, Ten Dam-van Loon Ninette H, Thiadens Alberta A H J, Meester-Smoor Magda A, de Jong-Hesse Yvonne, Los Leonoor I, den Hollander Anneke I, Boon Camiel J F, Kiemeney Lambertus A, van Eijk Kristel R, Bakker Mark K, Hoyng Carel B, Kuiper Jonas J W
Abstract excerpt
Importance: Idiopathic multifocal choroiditis (MFC) is poorly understood, thereby hindering optimal treatment and monitoring of patients. Objective: To identify the genes and pathways associated with idiopathic MFC. Design, Setting, and Participants: This was a case-control genome-wide association study (GWAS) and protein study of blood plasma samples conducted from March 2006 to February 2022. This was a...
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