Article

The <i>Coxiella burnetii</i> QpH1 plasmid is a virulence factor for colonizing bone marrow-derived murine macrophages

2020-03-25

Abstract excerpt

Coxiella burnetii carries a large conserved plasmid or plasmid-like chromosomally integrated sequence of unknown function. Here we report the curing of QpH1 plasmid from C. burnetii Nine Mile phase II, the characterization of QpH1-deficient C. burnetii in in vitro and in vivo infection models, and the characterization of plasmid biology. A shuttle vector pQGK, which is composed of the CBUA0036-0039a region (pred...

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Literature Corpus work: cbffd886-be62-5e21-b4cd-a3537a20251a
DOI: 10.1101/2020.03.22.001875

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