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Mitochondrial DNA is a target of HBV integration

3 Jul 2023

Abstract excerpt

Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear. In this study, we apply a high-throughput HBV integration sequencing approach that allows sensitive identification of HBV integration sites and enumeration of integration clones. We identify 3339 HBV...

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PMID: 37400627
DOI: 10.1038/s42003-023-05017-4

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