Article
Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels.
Channels (Austin, Tex.) - 1 Dec 2023
Mustafá Emilio R, Weiß Konstantin, Weiss Norbert
Abstract excerpt
Missense mutations in the human secretary carrier-associated membrane protein 5 (SCAMP5) cause a variety of neurological disorders including neurodevelopmental delay, epilepsy, and Parkinson's disease. We recently documented the importance of SCAMP2 in the regulation of T-type calcium channel expression in the plasma membrane. Here, we show that similar to SCAMP2, the co-expression of SCAMP5 in tsA-201 cells...
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