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Article

Significant hypomethylation of MMP9 gene promoter in patients with systemic lupus erythematosus

23 Jun 2023

Abstract excerpt

Objective Scholars are exploring novel diagnostic and prognostic biomarkers with higher sensitivity and specificity for systemic lupus erythematosus (SLE). In this regard, DNA methylation alterations have aroused attention. The association between the dysfunction of MMP9 and TNFAIP3 genes and SLE has been previously demonstrated. Therefore, in this study, we investigated the methylation level of MMP9 and TNFAIP3...

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PMID: 37353777
DOI: 10.1177/09612033231185618

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