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Elevated cell-free mitochondria DNA level of patients with premature ovarian insufficiency

22 Jun 2023

Abstract excerpt

BACKGROUND: Premature ovarian insufficiency (POI) patients present with a chronic inflammatory state. Cell-free mitochondria DNA (cf-mtDNA) has been explored as a reliable biomarker for estimating the inflammation-related disorders, however, the cf-mtDNA levels in POI patients have never been measured. Therefore, in the presenting study, we aimed to evaluate the levels of cf-mtDNA in plasma and follicular fluid...

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PMID: 37349693
DOI: 10.1186/s12884-023-05769-1

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