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A kaleidoscopic view of ovarian genes associated with premature ovarian insufficiency and senescence

7 Jul 2021

Abstract excerpt

Ovarian infertility and subfertility presenting with premature ovarian insufficiency (POI) and diminished ovarian reserve are major issues facing the developed world due to the trend of delaying childbirth. Ovarian senescence and POI represent a continuum of physiological/pathophysiological changes in ovarian follicle functions. Based on advances in whole exome sequencing, evaluation of gene copy variants,...

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PMID: 34233068
DOI: 10.1096/fj.202100756r

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